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Future Med Chem. From passengers to drivers: Impact of bacterial transposable elements on evolvability. Nucleic Acids Research DOI: Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs.


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Nature Genetics doi Genetic interactions reveal the evolutionary trajectories of duplicate genes. The Genetic Landscape of a Cell.

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Science PloS Biol. A critical view of metabolic network adaptations.

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HFSP J. Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks. Genome Biol. Co-regulation of metabolic genes is better explained by flux coupling than by network distance.

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PloS Comp. Metabolic reconstruction and analysis for parasite genomes.

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Trends Parasitol Chemical Reviews DOI: Plasticity of genetic interactions in metabolic networks of yeast. PNAS J, Oliver, S. Evaluation of predicted network modules in yeast metabolism using NMR-based metabolite profiling. Genome Res. An integrated view on protein evolution.

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Phenotypic activation to discover biological pathways and kinase substrates. Cell Cycle 5: Chance and necessity in the evolution of minimal metabolic networks. Nature Mapping pathways and phenotypes by systematic gene overexpression. Cell Adaptive evolution of bacterial metabolic networks by horizontal gene transfer.

Nature Genetics Horizontal gene transfer depends on gene content of the host. Bioinformatics: from molecules to systems. Papp, B. Genome-wide analysis of the context-dependence of regulatory networks. Genome Biology 6: Molecular chaperones as regulatory elements of cellular networks.

Current Opinion in Cell Biology Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast.

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Dosage sensitivity and the evolution of gene family size in yeast. Evolution of cis-regulatory elements in duplicated genes of yeast. Trends Genet.

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Genomic function: Rate of evolution and gene dispensability. Does the recombination rate affect the efficiency of purifying selection?

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The yeast genome provides a partial answer. Mol Biol Evol. Genetics Trends Ecol Evol

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